"It was first identified in the '70s, but research shows that skinny-jean syndrome (aka neuralgia paresthetica) is back. Symptoms are tingling or numbness of the thighs, caused when too-tight jeans press on the nerves at the top of the leg, and can be made worse by a skinny/stiletto combo. If you're suffering, stick to boyfriend jeans while the nerves repair themselves." British Cosmopolitan, September 2009.
Interesting, right? I'm about 90% sure that I have this. I mean, my jeans aren't super, super tight, but I often feel numbness and tingling, mostly tingling, in my thighs and I couldn't figure out what it was, now we know. I have skinny-jean syndrome. Awesome.